In this Research Spotlight episode, Dr. Yael Ben-Tal (Lloyd-Jones group, University of Edinburgh) joins us to share her work on the kinetics of a photoredox cross coupling using nickel and iridium.
Key reference:
J. Am. Chem. Soc. 2022, 144, 15372–15382.
https://doi.org/10.1021/jacs.2c06831
Other references (in order of appearance):
Original publications: Science. 2014, 345, 433-436.; Science. 2014, 345, 437-440.
Selected recent reviews: Chem. Rev. 2022, 122, 1485-1542.; Wiley Interdiscip. Rev. Comput. Mol. Sci. 2021, 12, e1573.; Angew. Chem. Int. Ed. 2019, 58, 6152-6163.; Eur. J. Org. Chem., 2020, 1327-1378.
Previous kinetic study: J. Am. Chem. Soc. 2020, 142, 11042-11049.
This design is adapted from that developed in J. Magn. Reson. 2013, 232, 39−44.
Original reaction developed in J. Am. Chem. Soc. 2016, 138, 8084-8087.
For more about isotope labelling in mechanistic study see Prog. Nucl. Magn. Reson. Spectrosc. 2022, 129, 28-106.