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DR TONY SETIOBUDI adalah dokter spesialis bedah tulang dan tulang belakang di Mount Elizabeth Hospital, Singapore. Beliau bekerja di SPRING HOPE ORTHOPAEDIC SPINE SURGERY di Paragon Medical. #VITAMINDDOSISTINGGI #DrTonySetiobudi #SpringHopeOrthopaedicSpineSurgery SPRING HOPE ORTHOPAEDIC SPINE SURGERY 290 Orchard Road #18-06 Singapore 238859 whatsapp: +65 9145 5793 (for appointment) Website : https://spring-hope.com Facebook : https://www.facebook.com/springhopeorthopaedic/ Time line: 0:10 Introduction 2:37 Keracunan vitamin D yang dilaportakan di US poison control centers tahun 2018 dan 2019 3:24 Apakah benar keracunan vitamin D hanya terjadi pada level di atas 300 ng/mL? 4:22 Fungsi vitamin D dan kalsium 5:08 Apa tanda terjadinya keracunan vitamin D? 6:03 Vitamin D overdosis dalam jangka panjang 7:05 Vitamin D Dosis berapa yang bisa menyebabkan keracunan? 7:48 No observed adverse effect level” atau (NOAEL) dari vitamin D 9:01 No observed adverse effect level” atau (NOAEL) dari Paracetamol 10:54 Apakah vitamin D 10,000 iu per hari, therapeutic effect nya lebih tinggi dari pada 2000 -3000 iu per hari? 12:32 Berapa kadar atau level vitamin D yang bisa menyebabkan keracunan? 15:22 Possible toxicity vitamin D di atas 100ng/mL dari hasil periksa darah 16:07 Hypercalcemia adalah medical emergency 18:08 Kesimpulan References: 1. 2019 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 37th Annual Report https://piper.filecamp.com/uniq/9ZN62pw4DkShNNNS.pdf 2. 2018 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 36th Annual Report https://piper.filecamp.com/uniq/meDKF2EpE2jsmTOs.pdf 3. NIH health information on vitamin D: https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/#h8 4. Paracetamol toxicology: https://echa.europa.eu/registration-dossier/-/registered-dossier/12532/7/1 5. Development of Vitamin D Toxicity from Overcorrection of Vitamin D Deficiency: A Review of Case Reports https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115827/pdf/nutrients-10-00953.pdf 6. "Excess gooD can be Dangerous". A case series of iatrogenic symptomatic hypercalcemia due to hypervitaminosis D https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476516/pdf/ccmbm-118-120.pdf